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Explore how artificial intelligence and quantum computing are revolutionizing scientific discovery and design in this commencement lecture delivered by IBM Fellow Dr. Alessandro Curioni at Imperial College London's Dyson School of Design Engineering. Discover the transformative potential of generative AI and quantum computers as they accelerate computations and enable scientists to represent previously unseizable problems in new and useful ways. Learn about the synergistic impact these technologies will have across all research areas and understand how they are becoming essential instruments for accelerated scientific discovery. Examine the critical role of collaboration between academia and industry in shaping a responsible and inclusive technological future, particularly as the Dyson School redefines engineering from making 'better things' to 'making things better.' Gain insights from Dr. Curioni's extensive experience in high-performance computing and computational science, including his work on complex problems in healthcare, aerospace, consumer goods, and electronics. Understand how rapid advances in digital innovation and AI are reshaping society and the importance of co-designing technology and human behavior to drive positive change for people and planet. The lecture addresses the two biggest transformations in computing in decades and their implications for addressing global challenges such as climate change and sustainability.