Deuterium Magnetic Resonance Imaging (dMRI) for Cancer and Immunotherapy

Learn about a groundbreaking functional MRI technique that uses oral deuterated water labeling followed by deuterium MRI (dMRI) for cancer diagnosis and treatment response assessment in this 31-minute webinar. Discover how this innovative approach differs from standard clinical imaging methods like FDG-PET/CT and conventional MRI by providing functional rather than purely anatomical imaging. Explore the safety and effectiveness of deuterated water, which is non-radioactive and safe to consume, as it preferentially labels highly proliferating cells including tumors to create enhanced dMRI signals compared to healthy tissues. Understand how this technique addresses the critical challenge of pseudo-progression, a false signal of tumor progression commonly seen with immunotherapy that can lead to premature discontinuation of effective treatments and unnecessary biopsies. Examine the clinical applications for central nervous system malignancies, including primary CNS lymphoma, and learn about the investigator-initiated clinical trial currently enrolling patients at Roswell Park Comprehensive Cancer Center. Gain insights into the translational research bridging pre-clinical models with clinical applications in pediatric cancer and immunotherapy, presented by a physician-scientist who holds a patent for this deuterium magnetic resonance imaging technology.