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Explore the principles of framework design for large JavaScript applications in this conference talk from JSConf Hawaii 2020. Delve into strategies for creating clean, stable, and developer-friendly software infrastructure that goes beyond off-the-shelf solutions. Learn how to design frameworks that developers will embrace, ensure rapid system stabilization, and apply key concepts such as tailoring, debugging, testability, empathy, and incremental adoption. Discover techniques for effective deployment, marketing, composition, and migration while addressing the challenges of uncertainty and temporary imperfection in framework development.