Cre-Lox System: Conditional Gene Knockout and Site-Specific Recombination

Explore the Cre-loxP system, a site-specific recombination technique used for conditional gene knockout, in this 12-minute educational video. Learn about the functionality of recombinase enzymes and how to create cell type-specific conditional knockouts using the Cre-loxP system. Discover the applications of spatiotemporal control in gene knockout experiments and understand how this system can be utilized to label cell types for morphological investigations. Gain insights into this integral experimental tool widely used in genetics and molecular biology research.

Syllabus

Intro
Cre-loxP system which is a SSR system is widely used as an integral experimental tool for generating the conditional mutant
How Recombinase enzymes works?
Creating cell type specific conditional Knockout using the Cre Lox P system
Spatiotemporal control of gene Knockout using the Cre Lox P system
Labeling cell types using the Cre Lox P system could be good strategy for investigating cell morphology
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