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Learn about building Atlas, the first open-source cloud-hosted genetic matching algorithm, in this technical conference talk that explores the development of a system for matching stem cell donors with blood cancer patients. Discover the history of stem cell donor matching and understand the complex algorithm that determines genetic compatibility between donors and patients. Explore critical technical challenges including memory management for storing nonillions of genotypes, scaling solutions for varying computational demands, and cloud service implementation for processing billions of genetic comparisons rapidly. Gain insights into the crucial role of domain expertise in software development, particularly when building systems that directly impact human lives through stem cell transplantation programs like Anthony Nolan's register which facilitates approximately 1,300 life-saving transplants annually.
