Cell Biology - Zellweger Syndrome, Refsum's Disease, Adrenoleukodystrophy

This lecture explains the structure and functions of peroxisomes, including lipid metabolism, catalase activity, and related biochemical pathways. It then connects peroxisomal deficiencies to Zellweger syndrome, Refsum disease, and adrenoleukodystrophy.

Syllabus

- Overview
- VLCFA, BCFA, & Peroxisome's ABCD1 Transporters
- F1: Beta-Oxidation of VLCFA Pathway OHOT
- F2: Alpha-Oxidation of BCFA Pathway
- F3: Ethanol Metabolism
- F4: Bile Acid Activation & Metabolism
- F5: Cholesterol Synthesis
- F6: Plasmalogen Synthesis
- F7: Catalase Activity for Reducing H2O2 Buildup
- Zellweger Syndrome
- Refssum's Disease
- Adrenoleukodystrophy ALD
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