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Explore circuit dynamics and cell-type-specific mechanisms in mouse models of Alzheimer's disease through this 39-minute research seminar. Learn from Dr. Ksenia Kastanenka of Mass General Brigham and Harvard Medical School as she presents cutting-edge findings on how different cell types contribute to neural circuit dysfunction in Alzheimer's pathology. Discover advanced techniques for probing cellular and circuit-level changes in disease models, understand the role of various brain cell populations in neurodegeneration, and examine how circuit dynamics are altered throughout disease progression. Gain insights into current research methodologies used to investigate cell-type-specific contributions to Alzheimer's disease pathophysiology and their implications for understanding disease mechanisms. This presentation is part of the BrainMap Seminar Series hosted by the MGH Martinos Center for Biomedical Imaging.
