Causal Mapping of Symptoms onto Human Brain Circuits
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Overview
Syllabus
Causal Mapping of Symptoms onto Human Brain Circuits
How do we localize neuropsychiatric symptoms?
Correlates of Psychiatric Disease
Lesion Localization
The human brain connectome
Lesion "Network" Localization
Lesion Network Mapping
Lesion mapping of depression (n = 461)
Therapeutic relevance of depression lesion network
Addiction Remission Targets
Causal sources of Information
DBS Network Mapping
"Individualized" TMS Network Mapping
Symptom-Specific TMS Targets?
Convergent Depression Circuit
Convergent Epilepsy Circuit
Conclusions
Acknowledgements Collaborators
Center for BRAIN CIRCUIT THERAPEUTICS
Taught by
MGH Martinos Center