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Explore how to accelerate life-saving innovation by overcoming systemic barriers and risk-averse funding models in this 50-minute conference talk from the 2025 Aspen Ideas Festival. Learn from leaders in science, global development, and emergency response as they examine what slows critical progress when speed is essential and share strategies for clearing pathways for transformative ideas. Discover how urgency, innovation, and strategic philanthropy can drive maximum impact in high-stakes situations where lives depend on rapid solutions. Gain insights into challenging outdated systems and fostering bold decision-making in fields where hesitation can have devastating consequences.