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Learn about antiviral medications specifically targeting Hepatitis C Virus (HCV) and Hepatitis B Virus (HBV) in this comprehensive 34-minute clinical pharmacology lecture. Explore the mechanisms of action, pharmacokinetics, pharmacodynamics, therapeutic applications, and side effects of anti-HCV and anti-HBV drugs used in clinical practice. Master the classification and clinical use of direct-acting antivirals (DAAs) for hepatitis C treatment, including protease inhibitors, polymerase inhibitors, and NS5A inhibitors, while understanding the therapeutic approaches for chronic hepatitis B management including nucleoside/nucleotide analogs and interferon-based therapies. Gain essential knowledge about drug interactions, contraindications, monitoring parameters, and treatment protocols for both HCV and HBV infections that is crucial for medical students preparing for MBBS examinations, USMLE Step 1, MRCP, and other medical licensing exams. Understand the evolution of hepatitis treatment from older interferon-based regimens to modern highly effective oral antiviral combinations, including cure rates, treatment duration, and patient selection criteria for optimal therapeutic outcomes.
