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Explore cutting-edge developments in gene therapy through this 52-minute webinar presented by GenScript's Roumen Bogoev, MSc, head of segment marketing with over 14 years of marketing experience and 15 years in research and development. Discover how gene therapy has evolved significantly with over 43 FDA-approved gene and cell therapies that have considerably impacted disease outcomes. Learn about non-viral gene editing technologies, particularly CRISPR, which has emerged as a pioneering technology allowing scientists to modify genes with unprecedented precision and ease. Understand the advantages of non-viral gene editing over viral-based approaches, including lower risk of immune system reactions and reduced potential for genetic material integration into patient DNA. Examine new CRISPR-based methodologies with increased specificity, such as Base and Prime editing, which are gaining traction in the field. Investigate the promising trend of using mRNA formats of CRISPR enzymes bundled with LNP delivery systems to efficiently edit genes without leaving lingering reagents and potentially introducing non-specific edits. Analyze more stable and higher-expression formats including self-amplifying and circular mRNA that are gaining popularity in therapeutic applications. Participate in live Q&A sessions to deepen your understanding of the latest advancements in CRISPR gene editing and targeted delivery solutions for gene therapy development.
