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Join immunologist John Tregoning in this 50-minute lecture from The Royal Institution as he explores the science behind aging, wellness, and mortality through personal experimentation. Discover how organs deteriorate with age, beginning with heart disease—the most common cause of death for middle-aged adults. Learn about the normal functioning of vital organs and how treatments have evolved for age-related conditions including stroke, dementia, diabetes, and cancer. Professor Tregoning, an expert in vaccine immunology at Imperial College London with over 20 years of research experience, debunks popular anti-aging "hacks" while sharing results from his own self-experimentation aimed at improving organ health and extending lifespan. This talk, recorded at the Ri on February 24, 2025, offers scientific insights from the author of "Live Forever? A Curious Scientist's Guide to Wellness, Disease and Ageing."