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Explore advanced three-dimensional cell culture methodologies for immuno-oncology research in this 57-minute webinar presented by Dr. Darryl Turner, Principal Scientist at Concept Life Sciences. Learn how to select optimal 3D co-culture systems that better model the complex in vivo tumor microenvironment compared to traditional two-dimensional monocultures. Discover the advantages and disadvantages of various 3D culture methods, with particular emphasis on incorporating fibroblasts and immune cells to create more physiologically relevant models. Understand how different cell types interact within co-cultures and influence treatment outcomes, gaining insights into analytical approaches for assessing multiple cell populations simultaneously. The presentation covers current methodologies employed at Concept Life Sciences for developing custom assays in autoimmunity and immuno-oncology, focusing on improving the translational relevance of immunological research. Gain practical knowledge about modeling cancer tissue complexity by incorporating various cell types including fibroblasts and immune cells, and learn how their interactions can impact patient treatment responses. The webinar provides valuable insights for researchers working in drug discovery and mechanistic studies who seek to enhance their in vitro models with greater biological complexity and clinical relevance.
