Class Central is learner-supported. When you buy through links on our site, we may earn an affiliate commission.

XuetangX

分子生物学

via XuetangX

Go to class Write review
Babbel Ad

You’re only 3 weeks away from a new language

Learn More → Boot.dev Ad

The Fastest Way to Become a Backend Developer Online

Learn More →

Overview

Google, IBM & Meta Certificates — All 10,000+ Courses at 40% Off
One annual plan covers every course and certificate on Coursera. 40% off for a limited time.
Get Full Access





《分子生物学》是生物科学专业的基础课，在整个生物科学专业的课程体系中，分子生物学的基本原理贯穿生物化学、遗传学、细胞生物学、生理学和发育生物学等，具有承上启下的作用。



Syllabus

  • 第1讲 课程导论 (Lecture 1. Introduction to the course)
    • 第2讲 DNA、RNA 与染色体结构 (Lecture 2. DNA, RNA, and chromosome structure)
      • 2.3　DNA 超螺旋 (DNA supercoiling)
      • 2.4 DNA 拓扑异构酶 (DNA topoisomerases)
      • 2.5 核小体与染色体结构 (Nucleosome and chromosome structure)
    • 第3讲 弱相互作用、蛋白质结构及蛋白质-DNA 相互作用 (Lecture 3. Weak Interactions, Protein Structures and Protein-DNA interaction)
      • 3.3 DNA-蛋白质相互作用 (DNA-proteins interaction)
    • 第4讲 分子生物学常用研究方法 (Lecture 4. Study genes and their products：methods in molecular biology)
      • 4.4 蛋白质研究方法 (Protein study)
      • 4.5 基因编辑 (Gene editing)
    • 第5讲 大肠杆菌 DNA 复制 (Lecture 5. DNA replication in E. coli)
      • 5.2 大肠杆菌 DNA 聚合酶 (DNA polymerase in E. coli)
      • 5.5 大肠杆菌 DNA 复制过程 (DNA replication in E. coli)
    • 第6讲 真核生物 DNA 复制 (Lecture 6. DNA replication in eukaryotes)
      • 6.1 真核生物DNA复制起点 (Replication origins in eukaryotes)
      • 6.2 真核生物DNA复制起始 (DNA replication initiation in eukaryotes)
      • 6.3 线性 DNA 末端复制问题 (The end replication problem for linear DNA)
    • 第7讲 DNA 突变与错配修复 (Lecture 7. DNA mutations and mismatch repair)
      • 7.2 DNA 突变原因 (Causes of DNA mutations)
      • 7.3  DNA 错配修复 (DNA mismatch repair)
    • 第8讲 碱基切除修复、核苷酸切除修复，及DNA跨损伤合成 (Lecture 8. Base excision repair and nucleotide excision repai, and translesion synthesis)
      • 8.1 核酸切除修复 (Nucleotide excision repair, NER)
      • 8.2 碱基切除修复 (Base excision repair, BER)
      • 8.3   跨损伤合成 (Translesion synthesis, TLS)
    • 第9讲 DNA双链断裂修复 (Lecture 9. DNA double-strand break repair, DSBR)
      • 9.1 DNA重组修复概述 (Overview of DNA recombinational repair)
      • 9.2 同源重组酶学机器（Enzymatic machineries of homologous recombination (HR)）
    • 第10讲 位点特异性重组 (Lecture 10. Site-specific recombination)
      • 10.1 位点特异性重组机制 (Mechanisms of site-specific recombination)
    • 第11讲 转座元件与转座 (Lecture 11. Transposable elements and transposition)
      • 11.2 转座元件分类与转座机制 (Category of TE and mechanisms of transposition)
    • 第12讲 转录 (Lecture 12. Transcription)
      • 12.1 启动子 (Promoter)
      • 12.3 原核生物转录起始 (Transcription initiation in prokaryotes)
      • 12.4 真核生物转录起始 (Transcription initiation in eukaryotes)
      • 12.6 转录终止 (Transcription termination)
    • 第13讲 RNA 剪接 (Lecture 13. RNA splicing)
      • 13.2 三类 RNA 剪接 (Three classes of RNA splicing)
      • 13.3 可变 mRNA 剪接 (Alternative mRNA splicing)
    • 第14讲 遗传密码与蛋白质合成（翻译）(Lecture 14. Genetic code and protein synthesis (Translation))
      • 14.1 遗传密码 (Genetic code)
      • 14.2 翻译组分 (The components of translation)
      • 14.3 翻译机制 (Translation mechanics)
    • 基因表达调控的基本原则 (Core principles of gene expression regulation)
      • 第15讲 细菌基因表达调控 (Lecture 15. Regulation of gene expression in bacteria)
        • 15.1 细菌转录起始调控 (Auto让egulation of transcription initiation in bacteria)
        • 15.2 细菌调控 RNA (Regulatory RNAs in bacteria)
        • 15.3 l噬菌体溶菌-溶原的调控 (Regulation of lysis-lysogeny decision of bacteriophage l)
      • 第16讲 真核生物基因表达调控 (Lecture 16. Regulation of gene expression in eukaryotes)
        • 16.1 真核转录调控基本机制 (Basic mechanisms of transcription regulation in eukaryotes)
        • 16.3 其他转录调控机制 (如绝缘子与 MAR) (Regulation of transcription by other mechanisms (e. g., insulator and MAR))
      • 第17讲 mRNA 稳定性、RNA 干扰（RNAi）与 mRNA 编辑 (Lecture 17. mRNA Stability, RNA Interference (RNAi), and mRNA Editing)
        • 17.1 mRNA 稳定性与缺陷 mRNA 的降解 (mRNA stability and degradation of defective mRNA)
        • 17.2 RNA 干扰、microRNA (miRNA) 的加工与功能 (RNA interference and the processing and function of microRNA (miRNA))
      • 第18讲 蛋白质合成的调控 (Lecture 18. Regulation of Protein Synthesis)
        • 18.1 翻译起始的调控 (Regulation of translation initiation)
      • 期末作业

        Taught by

        Southern University of Science and Technology

        Reviews

        Start your review of 分子生物学

        Go to class

        Never Stop Learning.

        Get personalized course recommendations, track subjects and courses with reminders, and more.

        Sign up for free
        Someone learning on their laptop while sitting on the floor.