免疫基因治疗

Learn about immunogene therapy through a comprehensive course covering five major areas: cytokines, antibody drugs, vaccines, cell therapy, and gene therapy. Explore the fundamentals of cytokines and their various types, followed by detailed study of antibody medications including molecular targeting antibodies, antibody-drug conjugates, and checkpoint inhibitors targeting PD-1 and CTLA-4. Master the principles of different vaccine types, including dendritic cell-based, vector-based, peptide-based, personalized neoantigen-based, and exosome-based tumor vaccines, along with HBV infection immunotherapy. Delve into cellular therapy focusing on CAR-T cells, their tumor antigens, chemotaxis, tumor microenvironment remodeling, resistance capabilities, and NK cell therapy. Conclude with gene therapy fundamentals, covering various gene transfer methods (physical and chemical), viral vectors (retroviral, adenoviral, lentiviral), and therapeutic strategies.