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This on-demand course equips students to understand, configure, and maintain multi-cluster Kubernetes infrastructures using Anthos GKE, and Istio-based service mesh, whether deployed with Anthos on Google Cloud or with Anthos deployed on VMware. This is the third, and final, course of the Architecting Hybrid Cloud Infrastructure with Anthos series. Completion of the Architecting with Google Kubernetes Engine path is a prerequisite for this course.