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NPTEL

Pharmaceutical Dosage Forms

NPTEL via Swayam

Overview

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ABOUT THE COURSE:The proposed course though a fundamental course is the core of pharmaceutical education and research. This course will provide a basic understanding of all the dosage forms which are being used in the treatment of diseases. The course is to be taken by the UG students to develop their understanding of the dosage forms and is also of benefit to PG students to further develop their understanding of the pharmaceutical dosage forms which they may take up for further research and development.INTENDED AUDIENCE: Pharmacy and allied fields

Syllabus

Week 1:Lecture 1: Introduction to Course and Course PlanLecture 2: Fundamentals of pharmaceutical processes- Unit operations- millingLecture 3: Fundamentals of pharmaceutical processes- Unit operations- mixingLecture 4: Fundamentals of pharmaceutical processes- Unit operations -clarificationLecture 5: Fundamentals of pharmaceutical processes- Unit operations –Drying
Week 2:Lecture 6: Fundamentals of pharmaceutical processes- Unit operations -CompactionLecture 7: Pharmaceutical RheologyLecture 8: Dosage form development: Pre-formulation studies-Bulk Characterization-ILecture 9: Dosage form development: Pre-formulation studies-Bulk Characterization-IILecture 10: Pre-formulation studies-Solubility and stability Analysis –I
Week 3:Lecture 11: Pre-formulation studies-Solubility and stability Analysis -IILecture 12: Biopharmaceutics and Pharmacokinetics Principles and PK modelsLecture 13: Biopharmaceutics and Pharmacokinetics: Factors affecting drug kineticsLecture 14: Biopharmaceutics and Pharmacokinetics:Dosage form design and evaluationLecture 15: Tablets: Types of tablets
Week 4:Lecture 16: Tablet design and ExcipientsLecture 17: Tablets: Granulation and compressionLecture 18:Evaluation of tablets and defectsLecture 19: Tablet coating: Types of coating and process of coatingLecture 20: Tablet coating: Evaluation and defects

Week 5:Lecture 21 Capsules: Hard Gelatin capsules and formulation componentsLecture 22:Soft gelatin capsules: formulation and evaluationLecture 23: Capsules: Evaluation and quality controlLecture 24:MicroencapsulationLecture 25: Sustained release dosage forms-I
Week 6:Lecture 26: Sustained release dosage forms-II Lecture 27: Sustained release dosage forms-IIILecture 28: Monophasic Liquid Dosage forms- Classification and ComponentsLecture 29: Monophasic Liquid Dosage forms- Formulation and EvaluationLecture 30: Pharmaceutical suspensions-Types and formulation excipients
Week 7:Lecture 31: Pharmaceutical suspensions- properties and evaluation
Lecture 32: Pharmaceutical Emulsion-types, theories of emulsificationLecture 33: Pharmaceutical Emulsion- formulationexcipients and evaluationLecture 34: Stability of Biphasic liquidsLecture 35: Semi Solid Dosage forms- Types and excipient selection

Week 8:Lecture 36: Semi Solid Dosage forms- properties, evaluation and stabilityLecture 37: Sterile products –ILecture 38: Sterile Products -IILecture 39: Suppositories-types, bases and propertiesLecture 40 :Suppositories-evaluation and stability

Week 9:
Lecture 41: Pharmaceutical aerosols- properties and excipientsLecture 42: Pharmaceutical aerosols- evaluation and stabilityLecture 43: Novel drug delivery systems –ILecture 44: Novel drug delivery systems –IILecture 45: Targeted drug delivery systems-I
Week 10:Lecture 46: Targeted drug delivery systems-IILecture 47: Targeted drug delivery systems-IIILecture 48: DissolutionLecture 49: Pilot plant scale up and Manufacturing design-ILecture 50: Sampling

Week 11:Lecture 51: Pharmaceutical Packaging: Types and Process-ILecture 52: Pharmaceutical Packaging: Types and Process-IILecture 53: Pharmaceutical Packaging: Types and Process-IILecture 54: Stability testing and kinetic principles: ILecture 55: Stability testing and kinetic principles: II

Week 12:Lecture 56: Concept of Statistical Quality Control
Lecture 57: Manufacturing Working Formula ProceduresLecture 58: Quality ManagementLecture 59: Drug Regulatory Affairs-ILecture 60: Drug Regulatory Affairs-II

Taught by

Prof. Ruchi Chawla

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