Broad Institute Courses

MPG Primer - Cellarium - 2024

Explore Cellarium's role in medical and population genetics, covering genetic variation, sequencing methods, and data analysis for complex trait research.

• YouTube
• 39 minutes
• Self-Paced
• Free Video

Introduction to Pharmacogenetics - MPG Primer 2024

Explore pharmacogenetics fundamentals, including genetic variation's impact on drug response, genotyping methods, and clinical applications in personalized medicine.

• YouTube
• 42 minutes
• Self-Paced
• Free Video

Alpha Missense: Proteome-Wide Missense Variant Effect Prediction

Explore Alpha Missense, an AI model predicting missense variant pathogenicity. Learn how it combines structural context and evolutionary conservation to achieve state-of-the-art results in genetic benchmarks.

• YouTube
• 1 hour 23 minutes
• Self-Paced
• Free Video

Scalable Single-Cell Models for eQTL Mapping - Primer and Main Talk

Explore scalable single-cell models for robust cell-state-dependent eQTL mapping. Learn about statistical challenges, computational solutions, and applications in identifying autoimmune disease risk loci in memory T cells.

• YouTube
• 1 hour 5 minutes
• Self-Paced
• Free Video

Decoding Cell Fates through Single Cell Genomics, Imaging, and Machine Learning

Explore decoding cell fates using single-cell genomics, imaging, and machine learning techniques in this cutting-edge symposium presentation by Dr. Jian Shu.

• YouTube
• 34 minutes
• Self-Paced
• Free Video

Linking Structure to Function in Metabolic and Blood Disorders Using Region Capture Micro-C

Explore linking structure to function in metabolic and blood disorders using Region Capture Micro-C, presented by PhD student Viraat Goel at the Broad Institute symposium.

• YouTube
• 34 minutes
• Self-Paced
• Free Video

Defining Disease Variant Function with Single Cell Multimodal Sequencing and Gene Editing

Explore disease variant function through single cell multimodal sequencing and gene editing techniques in this cutting-edge symposium presentation.

• YouTube
• 30 minutes
• Self-Paced
• Free Video

The Future of Human Genetics - Discussion and Opening Remarks

Explore the future of human genetics through expert discussions and insights from leading researchers at the Broad Institute's Variant to Function Symposium.

• YouTube
• 50 minutes
• Self-Paced
• Free Video

Variant-to-Function in Obesity Research: Challenges and Opportunities

Explore challenges and opportunities in obesity research through variant-to-function approaches with insights from a leading expert in genomic mechanisms of metabolic disease.

• YouTube
• 27 minutes
• Self-Paced
• Free Video

Neuronal Modeling and Therapeutic Profiling of Alterations to Genome Structure and Function

Explore neuronal modeling and therapeutic profiling of genomic alterations with insights from Michael Talkowski's research at the Broad Institute.

• YouTube
• 33 minutes
• Self-Paced
• Free Video

Moving from "Hit-or-Miss" Toward a Brighter Future for Psychiatric Diagnosis and Care

Explore new genetic and biological insights shaping the future of psychiatric diagnosis and care, offering hope for improved treatments in schizophrenia and bipolar disorder.

• YouTube
• 1 hour 4 minutes
• Self-Paced
• Free Video

Genomic Interpretation, seqr and Matchmaker Exchange - MPG Primer 2024

Explore genomic interpretation techniques, seqr software, and Matchmaker Exchange for advancing genetic research and diagnosis. Learn key tools for analyzing complex genetic data.

• YouTube
• 41 minutes
• Self-Paced
• Free Video

Structural Variation in Human Genomes - MPG Primer 2024

Explore structural variations in human genomes, their impact on genetics, and cutting-edge analysis techniques with experts from the Broad Institute.

• YouTube
• 45 minutes
• Self-Paced
• Free Video

SPLASH: Ultraefficient Statistics-First Analysis of Raw Sequencing Data - Lecture

Explore SPLASH, a revolutionary statistics-first approach for genomic analysis without reference genomes. Discover its efficiency in detecting diverse genetic mechanisms and its potential to transform genomic research and discovery.

• YouTube
• 1 hour 44 minutes
• Self-Paced
• Free Video

Models, Inference and Algorithms - Lightning Talks

Explore cutting-edge research in models, inference, and algorithms through lightning talks by five postdoctoral researchers at the Broad Institute of MIT and Harvard.

• YouTube
• 1 hour 26 minutes
• Self-Paced
• Free Video