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Explore cutting-edge advancements in genetic engineering for human T cell therapies in this 35-minute webinar presented by Dr. Theo Roth, MD, PhD. Delve into the development of non-viral genome targeting and pooled knockin screening, revolutionary methods that overcome traditional limitations in engineering primary human immune cells. Learn how these techniques enable rapid discovery of novel sequences for rewiring human immune cell genomes, paving the way for improved cellular therapies for solid tumors. Discover the high-throughput, modular platform that associates T cell genetic modifications with single-cell phenotypes across diverse disease contexts, leading to the identification of unique cell therapy targets with enhanced performance. Gain insights into the potential of these scalable genetic discovery systems to revolutionize the development of more effective and safer engineered cellular medicines.
