Explore the complex landscape of severe mental illness through this 48-minute conference talk from the Computational Genomics Summer Institute (CGSI) 2022. Delve into the research of Loes Olde Loohuis as she presents findings on disease trajectories of severe mental illnesses. Gain insights into the geospatial analysis that reveals distinct hotspots of severe mental illness, referencing the related paper available on medRxiv. Learn about the intersection of computational genomics and mental health research, and discover how these advanced techniques are contributing to our understanding of the progression and distribution of severe mental disorders.