The Hydrodynamics of Epithelial Tissues - From Symmetry to Cell Migration

Explore a 72-minute research seminar where Dr. Livio Carenza from Koç University delves into the hydrodynamics of epithelial tissues, focusing on their collective flow behavior in biological processes. Learn about a novel hydrodynamic framework that goes beyond traditional approaches to understand cellular dynamics, examining both nematic and hexatic symmetry in epithelial tissues. Discover how these different symmetries manifest at varying length scales, with nematic order dominating at larger scales and hexatic symmetry prevailing at smaller scales. Gain insights into the development of a hexanematic hydrodynamic theory that accounts for both the hexagonal geometry of small cell clusters and the uniaxial structure of global cellular flow, supported by experimental and numerical evidence. The presentation covers crucial applications in embryonic morphogenesis, wound healing, and cancer metastasis, offering a mathematical perspective on these biological phenomena.